Anti-Insulin (INS) Antibody ELISA Cov Khoom Siv

Anti-Insulin (INS) Antibody ELISA Kit Featured duab

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Cov khoom siv no yog siv rau qhov zoo hauv vitro nrhiav pom cov tshuaj tiv thaiv insulin hauv tib neeg cov ntshav.

Hauv cov tib neeg ib txwm muaj, muaj cov tshuaj tiv thaiv insulin hauv cov ntshav ua rau lawv muaj feem cuam tshuam rau hom 1 mob ntshav qab zib mellitus (T1DM). Anti-insulin antibodies yuav raug tsim tawm vim β-cell puas, yog li lawv qhov kev kuaj pom tuaj yeem ua tus cim ntawm autoimmune β-cell raug mob. Lawv kuj yog thawj cov cim tiv thaiv kab mob tshwm sim hauv cov menyuam yaus uas muaj kev pheej hmoo siab ntawm T1DM, thiab tuaj yeem siv rau kev kuaj pom ntxov thiab tiv thaiv T1DM, nrog rau muab qee yam kev taw qhia rau kev kuaj mob thiab kev kuaj mob ntawm T1DM.

Kev muaj cov tshuaj insulin hauv cov ntshav yog qhov tseem ceeb ua rau muaj kev tiv thaiv insulin. Cov neeg mob ntshav qab zib uas tau txais kev kho mob insulin tuaj yeem txhim kho cov tshuaj insulin vim yog kev tsim cov tshuaj tiv thaiv insulin, tshwj xeeb los ntawm kev siv tshuaj insulin ntau ntxiv tab sis tswj cov ntshav qabzib tsis zoo. Lub sijhawm no, cov tshuaj insulin yuav tsum tau kuaj; Cov txiaj ntsig zoo lossis nce titers tuaj yeem ua pov thawj lub hom phiaj ntawm insulin tsis kam. Tsis tas li ntawd, qhov kev kuaj pom no ua lub luag haujlwm pabcuam hauv kev kuaj mob ntawm Insulin Autoimmune Syndrome (IAS).

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Khoom cim npe

Txoj Cai

Cov khoom siv no kuaj pom cov tshuaj tiv thaiv-insulin antibodies (IgG) hauv tib neeg cov ntshav kuaj raws li txoj kev tsis ncaj ncees, nrog rau cov tshuaj purified recombinant tib neeg insulin siv los ua cov txheej txheem antigen.

Cov txheej txheem kev sim pib nrog kev ntxiv cov qauv ntshav rau cov tshuaj tiv thaiv qhov dej ua ntej coated nrog antigen, tom qab ntawd incubation. Yog tias cov tshuaj tiv thaiv insulin muaj nyob rau hauv cov qauv, lawv yuav tshwj xeeb khi rau cov coated recombinant tib neeg cov tshuaj insulin hauv cov qhov dej, tsim cov antigen-antibody complexes ruaj khov.

Tom qab ntxuav kom tshem tawm cov khoom tsis sib xws thiab tsis txhob cuam tshuam, cov enzyme conjugates ntxiv rau hauv qhov dej. Qhov thib ob incubation kauj ruam tso cai rau cov enzyme conjugates los khi tshwj xeeb rau cov antigen-antibody complexes uas twb muaj lawm. Thaum TMB substrate tov yog qhia, cov tshuaj tiv thaiv xim tshwm sim nyob rau hauv lub catalytic kev txiav txim ntawm lub enzyme nyob rau hauv lub complex. Thaum kawg, tus nyeem ntawv microplate yog siv los ntsuas qhov nqus (A tus nqi), uas ua rau kev txiav txim siab ntawm qhov muaj cov tshuaj tiv thaiv insulin hauv cov qauv.

Khoom nta

High rhiab heev, tshwj xeeb thiab stability

Khoom Specification

Txoj Cai	Enzyme txuas immunosorbent assay
Hom	Tsis ncajTxoj kev
Daim ntawv pov thawj	NMPA
Cov qauv	Tib neeg cov ntshav / ntshav
Specification	48T / hli96T
Cia kub	2-8℃
Txee lub neej	12hli